Recent Posts

Short tutorials on genomic and transcriptomic analyses. Downloading data download data from SRA download data from gemma Aligning …

Aligning with BWA References: https://www.broadinstitute.org/files/shared/mpg/nextgen2010/nextgen_li.pdf …

Aligning with STAR Get the latest version of STAR. All things STAR here: https://github.com/alexdobin/STAR. Precompiled binaries are …

Gene expression profiles that co-vary suggest co-regulation, co-function or co-localization. This pipeline involves the construction of …

Projects

Sex differences in disease

Many diseases affect men and women differently, but strikingly so in autoimmune disease.

Co-expression networks

When is co-expression real?

Gene expression analysis

Differential gene expression analysis of disease

X-interactome

Using co-expression to understand X chromosome gene interactions and regulation

X-marks the spot

The X-chromosome plays a major role in many diseases and disorders.

Recent Publications

Quickly discover relevant content by filtering publications.

The use of the human reference genome has shaped methods and data across modern genomics. This has offered many benefits while creating …

Differential expression (DE) is commonly used to explore molecular mechanisms of biological conditions. While many studies report …

Many tools are available for RNA-seq alignment and expression quantification, with comparative value being hard to establish. …

Single-cell RNA-sequencing (scRNA-seq) technology provides a new avenue to discover and characterize cell types; however, the …

Summary: Evaluating gene networks with respect to known biology is a common task but often a computationally costly one. Many …

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