Sara Ballouz
Sara Ballouz
Home
Posts
Projects
Publications
Contact
2
Candidate disease gene prediction using Gentrepid: application to a genome-wide association study on coronary artery disease
Current single-locus-based analyses and candidate disease gene prediction methodologies used in genome-wide association studies (GWAS) …
Sara Ballouz
,
Jason Y. Liu
,
Martin Oti
,
Bruno Gaeta
,
Diane Fatkin
,
Melanie Bahlo
,
Merridee A. Wouters
Cite
DOI
Identification of novel therapeutics for complex diseases from genome-wide association data
BACKGROUND: Human genome sequencing has enabled the association of phenotypes with genetic loci, but our ability to effectively …
Mani P. Grover
,
Sara Ballouz
,
Kaavya A. Mohanasundaram
,
Richard A. George
,
Craig D. H. Sherman
,
Tamsyn M. Crowley
,
Merridee A. Wouters
Cite
DOI
Gentrepid V2.0: a web server for candidate disease gene prediction
BACKGROUND: Candidate disease gene prediction is a rapidly developing area of bioinformatics research with the potential to deliver …
Sara Ballouz
,
Jason Y. Liu
,
Richard A. George
,
Naresh Bains
,
Arthur Liu
,
Martin Oti
,
Bruno Gaeta
,
Diane Fatkin
,
Merridee A. Wouters
Cite
DOI
Analysis of genome-wide association study data using the protein knowledge base
BACKGROUND: Genome-wide association studies (GWAS) aim to identify causal variants and genes for complex disease by independently …
Sara Ballouz
,
Jason Y. Liu
,
Martin Oti
,
Bruno Gaeta
,
Diane Fatkin
,
Melanie Bahlo
,
Merridee A. Wouters
Cite
DOI
Web tools for the prioritization of candidate disease genes
Despite increasing sequencing capacity, genetic disease investigation still frequently results in the identification of loci containing …
Martin Oti
,
Sara Ballouz
,
Merridee A. Wouters
Cite
DOI
Conditions for the evolution of gene clusters in bacterial genomes
Genes encoding proteins in a common pathway are often found near each other along bacterial chromosomes. Several explanations have been …
Sara Ballouz
,
Andrew R. Francis
,
Ruiting Lan
,
Mark M. Tanaka
Cite
DOI
Comparison of automated candidate gene prediction systems using genes implicated in type 2 diabetes by genome-wide association studies
BACKGROUND: Automated candidate gene prediction systems allow geneticists to hone in on disease genes more rapidly by identifying the …
Erdahl T. Teber
,
Jason Y. Liu
,
Sara Ballouz
,
Diane Fatkin
,
Merridee A. Wouters
Cite
DOI
Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events
Aims Cardiac electrical activity is extraordinarily robust. However, when it goes wrong it can have fatal consequences. Electrical …
Sara Ballouz
,
Melissa M Mangala
,
Matthew D Perry
,
Stewart Heitmann
,
Jesse A Gillis
,
Adam P Hill
,
Jamie I Vandenberg
Cite
«
Cite
×